91自拍
学术报告[2025]153号
(高水平大学建设系列报告1254号)
报告题目:Bayesian Structural Equation Multi-State Model for Mediation Analysis
报告人:王纯杰 教授(长春工业大学)
报告时间:2025年12月11日下午17:20-18:20
报告地点:#腾讯会议:673-683-763
报告内容:This study introduces a joint modeling framework that integrates structural equation modeling (SEM) with multi-state semi-competing risks models to investigate the complex causal mechanism among exposure, latent mediators, and multiple survival outcomes. The framework first employs a linear SEM to characterize latent mediators underlying highly correlated observable surrogates. These latent mediators are then incorporated into semi-parametric proportional hazards models with frailty to assess their mediating roles in the relationships between exposure and multiple correlated survival outcomes. Estimation and inference are conducted within an integrated Bayesian framework leveraging Monte Carlo methods, Gibbs sampling, and the Metropolis Hastings algorithm. Extensive simulation studies demonstrate the robustness and accuracy of the proposed method. Application to the Framingham Heart Study uncovers causal pathways linking smoking and metabolic health factors and evaluates their combined impact on long-term cardiovascular outcomes, offering new insights into the complex interplay between lifestyle factors and health risks.
报告人简历:王纯杰,教授,博士生导师,现任长春工业大学数学与统计学院院长,国务院政府特殊津贴获得者,吉林省杰青,吉林省长白英才领军人才,吉林省拔尖创新人才,也是国家一流专业负责人, 国家级一流课程主讲教师。省级黄大年教学科研团队负责人等。中国现场统计研究会理事,中国数学会概率统计研究会理事,全国工业统计学教学研究会常务理事,中国现场统计贝叶斯统计分会副理事长,中国现场统计研究会资源与环境统计分会副理事长,吉林省工业与应用数学研究会副理事长,吉林省现场统计研究会副理事长等。王纯杰教授在生物统计以及医疗、工业大数据,医疗影像分析方面研究并发表科研论文100余篇,其中SCI论文40篇。主持国家自然科学基金面上项目2项,青年基金项目1项,天元基金项目1项,吉林省重大汽车专项项目1项(300万)等。2022年获吉林省教学成果奖一等奖,2023年获吉林省自然科学二等奖。
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邀请人:91自拍
(周彦)
91自拍
2025年12月9日